mic index antibiosis effectmic mbc e coli atcc  (ATCC)

Journal: bioRxiv

Article Title: Nutrient-limited conditions reveal the activity of a minor groove binder, MGB-BP-3, against Escherichia coli

doi: 10.64898/2025.12.22.695926

Figure Lengend Snippet:

Article Snippet: The promising MIC against E. coli ATCC 25922 prompted us to assess MGB-BP-3 against a small panel of multi-drug-resistant clinical isolates ( ).

Techniques:

Journal: bioRxiv

Article Title: Nutrient-limited conditions reveal the activity of a minor groove binder, MGB-BP-3, against Escherichia coli

doi: 10.64898/2025.12.22.695926

Figure Lengend Snippet: Effect of calcium (Ca 2+ ), magnesium (Mg 2+ ) and ferrous (Fe 2+ ) concentrations on the antibacterial activity of MGB-BP-3 against E. coli ATCC 25922 in RPMI+10%LB. Increasing cation concentrations to 0.8 mM, 1.6 mM, and 3.2 mM resulted in higher MIC values, indicating reduced antibacterial activity of MGB-BP-3.

Article Snippet: The promising MIC against E. coli ATCC 25922 prompted us to assess MGB-BP-3 against a small panel of multi-drug-resistant clinical isolates ( ).

Techniques: Activity Assay

Journal: bioRxiv

Article Title: Nutrient-limited conditions reveal the activity of a minor groove binder, MGB-BP-3, against Escherichia coli

doi: 10.64898/2025.12.22.695926

Figure Lengend Snippet: Viable counts for cultures of E. coli 25922. Results are shown as No treatment control and cultures treated at 35±2° C for 24 hours, with MGB-BP-3 concentration corresponding to 0.5, 1, 5 and 10 times the MIC value determined.

Article Snippet: The promising MIC against E. coli ATCC 25922 prompted us to assess MGB-BP-3 against a small panel of multi-drug-resistant clinical isolates ( ).

Techniques: Control, Concentration Assay

Journal: bioRxiv

Article Title: Nutrient-limited conditions reveal the activity of a minor groove binder, MGB-BP-3, against Escherichia coli

doi: 10.64898/2025.12.22.695926

Figure Lengend Snippet: (a) Toxicity effects of MGB-BP-3 on G. mellonella larvae at various concentrations, monitored over 5 days. (b) Survival probability of G. mellonella larvae after 5 days of treatment with MGB-BP-3 following infection with 5×10 6 CFU/mL of E. coli ATCC 25922 strain. (c) Survival probability of G. mellonella larvae after 5 days of treatment with MGB-BP-3 following infection with 5×10 8 CFU/mL of S. aureus. Larvae were administered either PBS (control-treated) or MGB-BP-3 at various doses and incubated at 37°C. A single dose of the MGB-BP-3 treatment was given 2 hours post-infection. The number of surviving larvae was recorded every day for a total of 5 days. The uninfected PBS/PBS group represents larvae that were sham injected with sterile PBS (to serve as a control for the physical injection) and subsequently treated with sterile PBS. Statistical analyses were conducted using the log-rank test, with a significance level set at (p < 0.05) for multiple comparisons. All experiments were performed in triplicate, with a sample size of (n = 30)

Article Snippet: The promising MIC against E. coli ATCC 25922 prompted us to assess MGB-BP-3 against a small panel of multi-drug-resistant clinical isolates ( ).

Techniques: Infection, Control, Incubation, Injection, Sterility

Journal: Foods

Article Title: Optimizing Antibacterial Essential Oil Blends from Helichrysum plicatum , Petroselinum crispum , and Origanum vulgare for Dairy Preservation: Mixture Design and In Silico Analysis

doi: 10.3390/foods15040675

Figure Lengend Snippet: Intermolecular interactions in three and two-dimensional views for α-pinene ( A ), γ-curcumene ( B ), 1,3,8-p-menthatriene ( C ), and carvacrol ( D ) in complex with 6F86 protein from E. coli .

Article Snippet: MIC E. coli (ATCC 700728) , Model , DF , SS , MS , F , p -value.

Techniques: